Aiming at the highly difficult gas drainage and low efficient drivaging of low permeability coal seam drivaging process of a coal mine, CO₂ anti-reflection pre-splitting technology was put forward to improve seam permeability coefficient, gas drainage efficiency and working face drivaging efficiency. Rock mechanics simulation software was applied to simulate and analyze the coal damage distribution and stress distribution state in coal seam drivaging process. The simulation results showed that, the broken area on both sides of the roadway is 0~3m from one side, and the main stress concentrated area of roadway sides is 3~4m from roadway sides, the stress intensity ranges from 18 to 18.9 MPa in the drivaging process. Meanwhile, according to the simulated conclusions, detail parameters of pre-splitting and drainage drill holes were designed specifically. Field tests and effect analysis showed that, the net flow of gas drainage is increased by 27%, drainage concentration by 1.7 times, and desorption gas quantity is reduced from 7.27 m³/t to 4.3 m³/t in each dill site after pre-splitting, significantly improving the drivaging efficiency.