[1] Liu J N, Bu W B, Shi J L. Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia[J]. Chemical Reviews, 2017, 117(9):6160-6224.
[2] England C G, Hernandez R, Eddine S B Z, et al. Molecular Imaging of pancreatic cancer with antibodies[J]. Molecular Pharmaceutics, 2016, 13(1):8-24.
[3] Prodi L, Rampazzo E, Rastrelli F, et al. Imaging agents based on lanthanide doped nanoparticles[J]. Chemical Society Review, 2015, 44(14):4922-4952.
[4] Yu E Y, Bishop M, Zheng B, et al. Magnetic particle imaging:A novel in vivo imaging platform for cancer detection[J]. Nano Letters, 2017, 17(3):1648-1654.
[5] Terreno E, Castelli D D, Viale A, et al. Challenges for molecular magnetic resonance imaging[J]. Chemical Reviews, 2010, 110(5):3019-3042.
[6] Cai W, Gao H Y, Chu C C, et al. Engineering phototheranostic nanoscale metal-organic frameworks for multimodal imagingguided cancer therapy[J]. ACS Applied Materials & Interfaces, 2017, 9(3):2040-2051.
[7] Prantner A M, Yin C, Kamat K, et al. Molecular imaging of mesothelin-expressing ovarian cancer with a human and mouse cross-reactive nanobody[J]. Molecular Pharmaceutics, 2018, 15(4):1403-1411.
[8] Bhatnagar S, Verma K D, Hu Y, et al. Oral administration and detection of a near-infrared molecular imaging agent in an orthotopic mouse model for breast cancer screening[J]. Molecular Pharmaceutics, 2018, 15(5):1746-1754.
[9] Pati M L, Fanizza E, Hager S, et al. Quantum dot based luminescent nanoprobes for Sigma-2 receptor imaging[J]. Molecular Pharmaceutics, 2018, 15(2):458-471.
[10] Kunjachan S, Ehling J, Storm G, et al. Noninvasive imaging of nanomedicines and nanotheranostics:Principles, progress, and prospects[J]. Chemical Reviews, 2015, 115(19):10907-10937.
[11] He S S, Li C, Zhang Q F, et al. Tailoring platinum(IV) amphiphiles for self-targeting all-in-one assemblies as precise multimodal theranostic nanomedicine[J]. ACS Nano, 2018, 12(7):7272-7281.
[12] Sheng Z H, Hu D H, Zheng M B, et al. Smart human serum albumin-indocyanine green nanoparticles generated by programmed assembly for dual-modal imaging-guided cancer synergistic phototherapy[J]. ACS Nano, 2014, 8(12):12310-12322.
[13] Yu L X, Dong A J, Guo R W, et al. DOX/ICG coencapsulated liposome-coated thermosensitive nanogels for NIR-triggered simultaneous drug release and photothermal effect[J]. ACS Biomaterials Science & Engineering, 2018, 4(7):2424-2434.
[14] Fan W P, Yung B, Huang P, et al. Nanotechnology for multimodal synergistic cancer therapy[J]. Chemical Reviews, 2017, 117(22):13566-13638.
[15] Alivisatos P. The use of nanocrystals in biological detection[J]. Nature Biotechnology, 2004, 22:47-52.
[16] He C, Jiang S, Jin H, et al. Mitochondrial electron transport chain identified as a novel molecular target of SPIO nanoparticles mediated cancer-specific cytotoxicity[J]. Biomaterials, 2016, 83:102-114.
[17] Jana N R, Chen Y, Peng X. Size and shape-controlled magnetic (Cr, Mn, Fe, Co, Ni) oxide nanocrystals via a simple and general approach[J]. Chemistry of Materials, 2004, 16(20):3931-3935.
[18] Hao J J, Chen H L, Ren C L, et al. Synthesis of superparmagnetic Fe3O4 nanocrystals in reverse microemulsion at room temperature[J]. Materials Research Innovations, 2010, 14:324-326.
[19] Rockenberger J, Scher E C, Alivisatos A P. A new nonhydrolytic single-precursor approach to surfactant-capped nanocrystals of transition metal oxides[J]. Journal of the American Chemical Society, 1999, 121(49):11595-11596.
[20] Hyeon T, Lee S S, Park J, et al. Synthesis of highly crystalline and monodisperse maghemite nanocrystallites without a size-selection process[J]. Journal of the American Chemical Society, 2001, 123(51):12798-12801.
[21] Lee N, Yoo D, Ling D, et al. Iron oxide based nanoparticles for multimodal imaging and magnetoresponsive therapy[J]. Chemical Reviews, 2015, 115(19):10637-10689.
[22] Huang K C, Ehrman S H. Synthesis of iron nanoparticles via chemical reduction with palladium ion seeds[J]. Langmuir, 2007, 23(3):1419-1426.
[23] Huang, Wang L, Lin R, et al. Casein-coated iron oxide nanoparticles for high MRI contrast enhancement and efficient cell targeting[J]. ACS Applied Materials & Interfaces, 2013, 5(11):4632-4639.
[24] Li Z, Chen H, Bao H B, et al. One-pot reaction to synthesize water-soluble magnetite nanocrystals[J]. Chemistry of Materials, 2004, 16(8):1391-1393.
[25] Zhao N, Gao M. Magnetic janus particles prepared by a flame synthetic approach:Synthesis, characterizations and properties[J]. Advanced Materials, 2009, 21(2):184-187.
[26] Jia Q, Zeng J, Qiao R, et al. Gelification:An effective measure for achieving differently sized biocompatible Fe3O4 nanocrystals through a single preparation recipe[J]. Journal of the American Chemical Society, 2011, 133(48):19512-19523.
[27] Liu G, Gao J H, Ai H, et al. Applications and potential toxicity of magnetic iron oxide nanoparticles[J]. Small, 2012, 9(9/10):1533-1545.
[28] Liu J, Wang L Q, Cao J B, et al. Functional investigations on embryonic stem cells labeled with clinically translatable iron oxide nanoparticles[J]. Nanoscale, 2014, 6(15):9025-9033.
[29] Liu G, Wang Z Y, Lu J, et al. Low molecular weight alkylpolycation wrapped magnetite nanoparticle clusters as MRI probes for stem cell labeling and in vivo imaging[J]. Biomaterials, 2011, 32(2):528-537.
[30] Wang L Y, Huang J, Chen H B, et al. Exerting enhanced permeability and retention effect driven delivery by ultrafine iron oxide nanoparticles with T1-T2 switchable magnetic resonance imaging contrast[J]. ACS Nano, 2017, 11(5):4582-4592.
[31] Lin S Y, Huang R Y, Liao W C, et al. Multifunctional PEGylated albumin/IR780/iron oxide nanocomplexes for cancer photothermal therapy and MR imaging[J]. Nanotheranostics, 2018, 2(2):106-116.
[32] Li D L, Tan J E, Tian Y, et al. Multifunctional superparamagnetic nanoparticles conjugated with fluorescein-labeled designed ankyrin repeat protein as an efficient HER2-targeted probe in breast cancer[J]. Biomaterials, 2017, 147:86-98.
[33] Lin L S, Cong Z X, Cao J B, et al. Multifunctional Fe3O4@Polydopamine core-shell nanocomposites for intracellular mRNA detection and imaging-guided photothermal therapy[J]. ACS Nano, 2014, 8(4):3876-3883.
[34] Wang J Q, Liu H, Liu Y, et al. Eumelanin-Fe3O4 hybrid nanoparticles for enhanced MR/PA imaging-assisted local photothermolysis[J]. Biomaterials Science, 2018, 6(3):586-595.
[35] Liu H, Chen X, Xue W, et al. Recombinant epidermal growth factor-like domain-1 from coagulation factor VⅡ functionalized iron oxide nanoparticles for targeted glioma magnetic resonance imaging[J]. International Journal of Nanomedicine, 2016, 11:5099-5108.
[36] Zhou Z, Tian R, Wang Z Y, et al. Artificial local magnetic field inhomogeneity enhances T2 relaxivity[J]. Nature Communications, 2017, 8:15468.
[37] Zhao Z, Zhou Z, Bao J, et al. Octapod iron oxide nanoparticles as high-performance T2 contrast agents for magnetic resonance imaging[J]. Nature Communications, 2013, 4:2266.
[38] Ma T, Hou Y, Zeng J, et al. Dual-ratiometric target-triggered fluorescent probe for simultaneous quantitative visualization of tumor microenvironment protease activity and pH in vivo[J]. Journal of the American Chemical Society, 2018, 140(1):211-218.
[39] Guthi J S, Yang S G, Huang G, et al. MRI-visible micellar nanomedicine for targeted drug delivery to lung cancer cells[J]. Molecular Pharmaceutics, 2010, 7(1):32-40.
[40] Fan C H, Cheng Y H, Ting C Y, et al. Ultrasound/Magnetic targeting with SPIO-DOX-microbubble complex for imageguided drug delivery in brain tumors[J]. Theranostics, 2016, 6(10):1542-1556.
[41] Yang C X, Lin G, Zhu C Q, et al. Metalla-aromatic loaded magnetic nanoparticles for MRI/photoacoustic imaging-guided cancer phototherapy[J]. Journal of Materials Chemistry B, 2018, 6(17):2528-2535.
[42] Lin G, Zhang Y, Zhu C Q, et al. Photo-excitable hybrid nanocomposites for image-guided photo/TRAIL synergistic cancer therapy[J]. Biomaterials, 2018, 176:60-70.
[43] Liu G, Xie J, Zhang F, et al. N-Alkyl-PEI-functionalized iron oxide nanoclusters for efficient siRNA delivery[J]. Small, 2011, 7(19):2742-2749.
[44] Huang R Y, Chiang P H, Hsiao W C, et al. Redox-sensitive polymer/SPIO nanocomplexes for efficient magnetofection and MR imaging of human cancer cells[J]. Langmuir, 2015, 31(23):6523-6531.
[45] Chen S Z, Chen S Y, Zeng Y, et al. Size-dependent SPIONs dictate IL-1β release from mouse bone marrow-derived macrophages[J]. Journal of Applied Toxicology, 2018, 38(7):978-986.
