专题论文

角膜力学生物学研究进展

  • 李晓娜 ,
  • 魏俊超 ,
  • 王晓君 ,
  • 陈维毅
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  • 1. 太原理工大学应用力学与生物医学工程研究所, 太原 030024;
    2. 太原理工大学力学学院, 材料强度与结构冲击山西省重点实验室, 太原 030024;
    3. 太原理工大学力学国家级实验教学示范中心, 太原 030024
李晓娜,副教授,研究方向为眼力学生物学,电子信箱:lixiaona@tyut.edu.cn

收稿日期: 2018-05-08

  修回日期: 2018-05-30

  网络出版日期: 2018-07-23

基金资助

山西省重点研发计划国际科技合作项目(201703D421019);国家自然科学基金项目(11572213);山西省自然科学基金项目(201701D121144)

Advances in corneal mechanobiology

  • LI Xiaona ,
  • WEI Junchao ,
  • WANG Xiaojun ,
  • CHEN Weiyi
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  • 1. Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China;
    2. Shanxi Key Laboratory of Material Strength & Structural Impact;College of Mechanics, Taiyuan University of Technology, Taiyuan 030024, China;
    3. National Demonstration Center for Experimental Mechanics Education, Taiyuan University of Technology, Taiyuan 030024, China

Received date: 2018-05-08

  Revised date: 2018-05-30

  Online published: 2018-07-23

摘要

作为眼屈光系统的重要组成部分,角膜组织在眼内压的作用下,受到复杂载荷作用,角膜细胞能够感受力学刺激并做出积极响应。本文通过分析角膜组织的受力情况,综述了力学刺激下角膜细胞的生物学响应及其与角膜损伤修复和相关眼疾患之间的关系。

本文引用格式

李晓娜 , 魏俊超 , 王晓君 , 陈维毅 . 角膜力学生物学研究进展[J]. 科技导报, 2018 , 36(13) : 18 -22 . DOI: 10.3981/j.issn.1000-7857.2018.13.002

Abstract

As an important part of the ocular dioptric system, the corneal tissue is subject to the load under intra-ocular pressure. Corneal cells can sense and respond positively to the mechanical stimulation. In this paper, we review force analysis of corneal tissue borne, biological response of corneal cells to mechanical stimulation, and the relation with the repair after injury and relative diseases.

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